Researchers tested VER-01, a cannabis-based extract, on adults with chronic lower back pain worldwide.
Patients taking VER-01 reported major drops in pain scores compared to those on a placebo treatment.
After three months, participants on VER-01 reduced pain ratings by 1.9 points, while placebo patients dropped only 0.6.
During a six-month extension, VER-01 users saw further pain reductions and better sleep and physical function.
Safer Alternative to Risky Options
Chronic lower back pain affects 619 million people globally, making it the world’s leading disability.
Current therapies remain limited, with opioids risking addiction and NSAIDs causing heart or stomach complications.
VER-01 offered pain relief without dependency risks, though some patients reported dizziness, nausea, or heavy sleepiness.
Scientists observed no signs of abuse, unlike opioids, suggesting cannabis extract could provide a safer option.
Experts Urge Caution on Cannabis Use
VER-01 comes from Cannabis sativa and contains 2.5 milligrams of THC with other natural compounds.
Experts warned patients not to self-treat with marijuana, since smoking differs completely from VER-01 therapy.
Neuroscientist Jan Vollert stressed the distinction, comparing Nutella to hazelnuts as an analogy for differences.
Researchers plan further studies comparing VER-01 directly with opioid treatments for chronic lower back pain.
